Lub ntsiab lus kho mob ntawm AFP, lossis alpha-fetoprotein, nyob ntawm cov ntsiab lus uas nws ntsuas. Nov yog qee lub ntsiab lus kho mob tseem ceeb ntawm AFP:
1. Kev kuaj xyuas cov ntshav AFP cov ntsiab lus hauv cov menyuam yaus: nce AFP cov ntsiab lus hauv daim siab mob qog noj ntshav, hepatoblastoma, gonadal oblastoma, kab mob siab, thiab lwm yam.
2. Kev kuaj xyuas cov ntshav AFP cov ntsiab lus hauv cov neeg laus: AFP cov ntsiab lus tau nce hauv 60 feem pua ~ 70 feem pua ntawm cov neeg mob uas muaj mob qog noj ntshav thawj zaug, nrog rau cov neeg mob qog nqaij hlav qog nqaij hlav, qog zes qe menyuam, malignant teratoma, mob qog nqaij hlav pancreatic, mob plab, mob plab hnyuv thiab mob ntsws cancer.
3. Hauv cov neeg mob uas muaj kab mob siab zoo xws li mob siab thiab mob siab thiab mob cirrhosis, ntshav AFP qib nce mus rau qib sib txawv, tab sis feem ntau ntawm lawv qis dua 1000ug / L, uas cuam tshuam rau qib ntawm daim siab cell necrosis thiab rov tsim dua tshiab.
4. Qhov nce ntawm AFP nyob rau hauv cov kab mob siab benign yog ib ntus thiab kav ntev li 2-3 lub lis piam. Cov qog nqaij hlav qog nqaij hlav tsis tu ncua. Yog li ntawd, kev soj ntsuam zoo ntawm AFP cov ntsiab lus tsis tuaj yeem tsuas yog sib txawv ntawm daim siab mob siab los ntawm cov kab mob siab, tab sis kuj kuaj mob qog noj ntshav hauv lub siab thaum ntxov.
5. Nyob rau hauv physiological tej yam kev mob, alpha-fetoprotein yog secreted los ntawm cov me nyuam yug tshiab naive hepatocytes, thaum fetal hepatocytes tsis tau tag nrho tsim (differentiated). Tus nqi ntawm alpha-fetoprotein secreted yog loj, uas tuaj yeem nkag mus rau hauv niam cov ntshav los ntawm cov ntshav qaum, yog li cov poj niam cev xeeb tub thaum cev xeeb tub yuav zoo rau alpha-fetoprotein.
