NGAL yog Neutrophil gelatinase-associated lipocalin luv luv, NGAL yog ib qho ntawm cov lipid carrier proteins. Cov kev tshawb fawb tsis ntev los no tau tshawb pom tias NGAL yog qhov qhia ntxov ntawm ob qho tib si mob ntshav qab zib nephropathy thiab mob raum puas. NGAL ua haujlwm ntau yam, suav nrog kev khi thiab thauj cov hydrophobic me me molecules, koom nrog hauv cov teeb liab hloov, o, kev loj hlob ntawm embryonic, kev tiv thaiv kab mob, thiab kev tshwm sim thiab kev loj hlob ntawm cov qog nqaij hlav sib txawv. Kev kuaj ntshav thiab zis tuaj yeem siv los txheeb xyuas NGAL.
NGAL yog ib qho molecule siv los kuaj xyuas AKI, tsis zoo li cov txheej txheem kuaj mob ntawm tus qauv ntsuas. Raws li ntau tus kws tshawb fawb, ntawm ntau qhov ntsuas, NGAL yog qhov kev kwv yees zoo tshaj plaws ntawm AKI. Qhov nruab nrab ntawm NGAL hauv cov neeg noj qab haus huv cov zis yog 5.3ng / mL (ntau: 0 7-9.6ng/mL), thaum qhov nruab nrab ntawm lawv cov ntshav yog 63ng / mL (ntau: { {6}}ng/mL). NGAL qib nce nrog raum puas (hauv 2h). Qhov nruab nrab plasma concentration ntawm NGAL yog li ntawm 25ng / mL mus rau 3491ng / mL, thiab cov concentration ntawm NGAL nyob rau hauv cov zis ntawm random xaiv ICU cov neeg mob nyob ntawm 110ng / mL mus rau 40000ng / mL. Thaum cov ntshav plasma lossis zis NGAL ntau dua 400ng / mL, lub raum tsis ua haujlwm tau txiav txim siab tias tam sim no.
Singclean Neutrophil Gelatinase-Associated Lipocalin (NGAL) Cov Khoom Siv Kev Ntsuas Ceev (Colloidal Kub) siv cov ntawv sau npe colloidal kub thiab tiv thaiv kab mob chromatography raws li lub hauv paus ntsiab lus ntawm ob-antibody Sandwich txoj kev xaiv los kuaj xyuas qib siab ntawm NGAL hauv cov zis. Thaum kuaj, cov zis tso zis txav mus los ntawm kev ua capillary.
