Hauj lwm lawm

Kev tsis

Ceev ceev^®yog ib qho tsis muaj menyuam, tsis yog -pyrogenic, siab-molecular- hnyav sodium hyaluronate gel qhia rau kev kho mob hauv caug osteoarthritis (OA) cov tsos mob. Kev tswj hwm los ntawm kev txhaj tshuaj intra- articular txhaj, nws rov kho cov viscoelasticity ntawm cov kua dej synovial- muab lubrication, poob siab, thiab kev mob nyem.

High purity, ntuj.

Siab viscoelasticity, 1.1-2.1 lab Daltons.

Muaj kev nyab xeeb thiab biocompatible heev

Tso qhov mob

Khoom	Paub meej
Cov khoom xyaw nquag	Sodium Hyaluronate (los ntawm streptococcal fermentation)
Qhov tshwm sim	Sterile, pob tshab, viscoelastic gel
Molecular Luj	1.1-2.1 lab Daltons (siab viscoelasticity)
Muaj Concentrations	10 mg/mL (1.0%), 12 mg/mL (1.2%), 20 mg/mL (2.0%)
Muaj Volumes	1.0 mL, 2.0 mL, 2.5 mL, 3.0 mL
Cia	Chav tsev kub, tiv thaiv lub teeb
Kev tswj hwm	Intra-kev txhaj tshuaj articular los ntawm kws kho mob

Osteoarthritis (OA) yog ib qho kab mob sib koom ua ke degenerative uas tshwm sim los ntawm kev poob ntawm pob txha pob txha. Raws li OA nce ntxiv, cov kua dej synovial- uas ib txwm muaj hyaluronic acid- poob nws cov khoom viscoelastic, ua rau:

Mob thiab txhav

o thiab mob

Txo kev txav mus los thiab kev sib koom ua haujlwm

Cov neeg laus

Ua ntej kev raug mob los yog raug mob

Obesity thiab mechanical overload

Genetic predisposition

Hyaluronic acid (HA) yog ib qho tseem ceeb ntawm cov kua synovial, muab:

Lubrication:Txo kev sib txhuam ntawm cov pob txha mos thaum lub sij hawm sib koom ua ke

Shock Absorption:Tiv thaiv pob txha mos los ntawm txhua yam kev nyuaj siab

viscosity:Txhim kho cov kua dej sib xws rau kev sib koom ua ke

Hauv OA, HA concentration thiab molecular hnyav txo. Exogenous HA txhaj tshuaj kho cov khoom no, txo qhov mob, txhim kho kev txav mus los, thiab tiv thaiv pob txha mos.

Ceev ceev^®ua haujlwm dhau losviscosupplementation- ntxiv cov HA depleted hauv OA pob qij txha. Exogenous HA:

Restores synovial kua rheology thiab viscoelasticity

Muab tam sim ntawd lubrication thiab cushioning

Txo cov kab mob synovial

Tiv thaiv articular pob txha mos los ntawm kev degradation ntxiv

Stimulates endogenous HA ntau lawm

Txawm hais tias exogenous HA muaj qhov txwv tsis pub nkag mus rau -ib nrab ntawm lub neej-, nws cov txiaj ntsig kho mob tuaj yeem nyob mus txog 6 lub hlis lossis ntev dua.

Nco ntsoov	Volume Options	Pom zoo Regimen
10 mg / ml (1.0%)	1.0 mL, 2.0 mL, 2.5 mL	Ib qho kev txhaj tshuaj rau 3-5 lub lis piam
12 mg / ml (1.2%)	1.0 mL, 2.0 mL, 2.5 mL	Ib qho kev txhaj tshuaj rau 3-5 lub lis piam
20 mg / ml (2.0%)	2.0 mL, 3.0 mL	Kev txhaj tshuaj ib zaug(ib yam kev kho mob)

Qhov tseem ceeb Distinction:20 mg/mL formulation muab ib zaug - txhaj tshuaj yooj yim nrog piv rau ntev - kev ua tau zoo, txhawb kev rov qab sai dua thiab txhim kho cov neeg mob ua raws.

Kawm Tsim:Tag nrho ntawm 300 tus neeg mob nrog lub hauv caug OA tau cuv npe hauv kev tshawb fawb soj ntsuam ua ntawmThawj Tsev Kho Mob ntawm Zhejiang Suav Medical UniversitythiabTongde Tsev Kho Mob ntawm Zhejiang Xeev(ob lub tsev kho mob Qib A hauv Suav teb).

Cov txiaj ntsig (6-hli tom qab):